Acute disseminated encephalomyelitis after SARS-CoV-2 vaccination

Clin Neurol Neurosurg. 2021 Sep:208:106839. doi: 10.1016/j.clineuro.2021.106839. Epub 2021 Jul 21.

Abstract

Several central and peripheral nervous system complications associated with the severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection have been recently described. An effective mass vaccination program is necessary to effectively reduce infection spread and, consequently, limit long-term sequelae, including those affecting the nervous system. Nevertheless, as more patients gain access to coronavirus disease 2019 (COVID-19) vaccines, it is important to report potential adverse events. Herein, we report a patient with previous history of post-infectious rhombencephalitis who developed an acute disseminated encephalomyelitis (ADEM) two weeks after being vaccinated for COVID-19.

Keywords: COVID-19; Encephalitis; Neurological adverse events; Neurological complications; Vaccine.

Publication types

  • Case Reports

MeSH terms

  • BNT162 Vaccine
  • COVID-19 / prevention & control*
  • COVID-19 Vaccines / adverse effects*
  • Female
  • Humans
  • Middle Aged
  • Myelitis, Transverse / etiology*
  • SARS-CoV-2

Substances

  • COVID-19 Vaccines
  • BNT162 Vaccine