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The International Ecclesiastical College Sedes Sapientiae is a seminary in Rome erected by the Holy See and intended for the formation of candidates to the priesthood coming from dioceses of the world.

In October 1990, Bishops, united in a synod with the Pope, underscored the urgent need to promote priestly vocations and to ensure a solid intellectual and spiritual formation for aspirants to the priesthood.

The direction of the Ecclestiastical College is entrusted to the 

Prelature of Opus Dei.