Dr SABINE PALIARD-FRANCO HEALED 100% of his PATIENTS ATTAINED from the CORONAVIRUS 2/2
Dr SABINE PALIARD-FRANCO HEALED 100% OF HIS PATIENTS ATTAINED FROM THE CORONAVIRUS
- II -
FEEDBACK on the management of SICK SUSPECTS FROM COVID 19: GROUP I MEDICAL OFFICE OF CHABONS. Dr Sabine PALIARD-FRANCO (March 29, 2020)
Following my communication of March 26, 2020 concerning suspected patients with severe Covid-19 (from group II) you will find below the graphs showing the evolution of the symptoms of the 24 patients having had a moderate form of atypical (group I) influenza-like illness, and for which I thought they should still receive treatment and close monitoring:
The criteria for initiating treatment are as follows: Duration of evolution greater than 5 days, persistent dry cough, dyspnea (Shortness of breath (SOB)), marked general signs, prolonged fever, relapse of cough after a semblance of healing in the 2nd week between D7 and D10... Respiratory risk factors and cardiovascular, autoimmune disease, cancer. Smoking, overweight. Allergic terrain. Context social.
The patients all received at least one Macrolide (Zithromax, Zeclar, Rulid or Josacine) and in thecases with poorly tolerated pneumonitis, a combination with C3G (CEFTRIAXONE) or Cefpodoxime.
I prescribed macrolide alone to patients in whom I noticed the existence of a syndrome bronchial with atypical pneumonia, bilateral, with reduction of the vesicular murmur and dyspnea, and an additional C3G in case of marked ENT signs or lower lung infections, frank acute lobar. Because we observe during this flu syndrome an attack of the whole tree respiratory at different levels.
We followed the patients every day and noted the symptoms state, at the start of the disease, on the day ofinitiation of treatment (noted T) and the following 3 days (T1, T2, T3).
The symptoms studied are cough, fever, dyspnea, asthenia, digestive disorders, headache and ENT signs (sore throat, nasal blockage, anosmia and ageusia).
Cough group I :
(onset of symptoms)
After initiation of treatment at time T, the rapidly progressive disappearance of cough: 50% of patients no longer have a cough within 24 hours, and no one complains of a cough at 72 hours.
The fight against this symptom contributing to the reduction of the risk of contagion by projection of droplets.
Fever group I :
Moderate fever is observed before treatment. It normalizes within 48 hours under treatment.
Intense dyspnea Group I :
The main symptom being shortness of breath, we observe, shortly after the initiation of treatment, rapid improvement in exercise dyspnea.
Asthenia Group I :
In just 24 hours of treatment, fatigue decreases markedly, most patients finding a much better overall condition.
ENT group I :
ENT signs such as sore throat or nasal blockage decrease very strongly at 48 hours after the start of treatment.
Digestive group I :
Patients with initial digestive disorders such as abdominal pain febrile, septic syndrome, diarrhea or vomiting, received:
- or a fluoroquinolone more focused on colonic symptoms.
- either a macrolide if they had secondary respiratory signs after the crisis digestive past.
Group I headache :
Headaches present in 1/3 of patients give way in just 24 hours of treatment in 3 patientsin 4 and in all patients in 3 days.
Myalgia Group I :
Almost 50% of patients had muscle or joint pain.
Myalgia being an alarm signal in patients, associated with a decline in general health, and anxiety frequently, give way within 48 hours with treatment.
Various points:
1) Note that not all patients were treated at the same stage of the disease (between D5 and D20)
2) It is noteworthy that patients have many symptoms which all yield within the same 48h period, which therefore rules out the hypothesis of a simple natural elimination of the virus in this healing process.
3) The patients for whom we have the most perspective no longer have symptoms.
4) I used 4 different macrolides, and didn't notice any difference in effectiveness, but only digestive tolerance.
Conclusion :
Covid-19, this coronavirus from the Orient that has been occupying us for several months all over the World, generates anguish in billions of confined people, causes human damage and considerable economic impact, even in developed countries which had not seen the coming disaster.
This communication from a general practitioner was not premeditated, especially in these times when weare overwhelmed with work. It was made in an emergency because it should not be kept for himself.
Even in a very unacademic way, it seemed important to me, in this very particular context to share with my colleagues as soon as possible good results of an empirical treatment on a highly contagious disease, still poorly understood and leading to atypical pneumonia sometimes serious and fatal.
This clinical study shows the rapid response of highly suspect patients of covid 19 to a very simple protocol: taking a macrolide given alone in group I or combined with a C3G in group II, which seems, on the one hand, to stop the deterioration of the disease, and on the other hand, effectively treat all of its symptoms within 24 or 48 hours.
This is surprising and raises many questions:
Indeed, it would be interesting to know if the macrolide also has a virucidal action even moderate, in addition to its activity against bacterial superinfection and the ensuing inflammation.
The Zithromax for its part was the subject of Japanese work in October 2019 which proved its virucidal action on the H1N1 virus, with a good description of its mechanism for combating intra-cellular infections. pubmed.ncbi.nlm.nih.gov/31300721/
Would this anti-viral activity also apply to the coronavirus?
It would be interesting to understand if certain macrolides actually have properties virucidal, if some would be more effective than others, or if it is simply class effect. This last hypothesis seems to be confirmed given the equivalence of efficiency on the symptoms when we vary the molecules.
Which would have the advantage of sheltering from a possible shortage of macrolide drugs if they were in great demand.
It is therefore necessary to determine whether to continue antibiotic therapy while viral excretion persists. A minimum treatment time of 10 to 14 days seems indicated to avoid relapses of these atypical lung diseases.
To date, it is very reassuring to note that all the patients I have received with these symptoms are responders to the Macrolide protocol alone (group I) or Macrolide-C3G for severe forms (group II). (around forty patients as of March 28, 2020 and this is constantly growing)
The current pandemic and the peak epidemic which arrives in our country need to react quickly to avoid hospitalizations, and congestion in hospitals.
Considering :
1 / the relative safety of macrolides and cephalosporins, old and well-known drugs known, obviously with respect to contraindications,
3 / their easy access to City Medicine or to the Hospital,
4 / pending validated, safe or innovative active molecules and a vaccine
5 / the benefit-risk ratio being clearly favorable,
6 / when hydroxychloroquine is not possible in certain patients or poorly tolerated
7 / it would undoubtedly be beneficial to immediately benefit those affected by this viruses, especially the most vulnerable, elderly, who are unfortunately variable in adjustment in this pandemic period.
I have not tested the injectable forms of macrolides (Erythromycin, Rovamycin), which could be useful to the elderly or dependent. This simple drug is certainly not not the first envisaged in hospital structures accustomed to using molecules with more broad spectrum, but it could regain its place in this epidemic context.
It is important that other colleagues engage in this process to apply this protocol and communicate their results to support this analysis. The risk to patients is low, on the other hand, the expected benefit is significant in the absence of validated specific treatment for covid-19. Because it is obvious that the procedures initiated by the authorities cause delays which are not adapted to the urgency of the situationon the ground, which requires applicable solutions at once.
And this, to avoid loss of chance and save human lives when we start to glimpse active treatments.
Prospective studies should be undertaken, by testing patients in nursing homes or hospital services and would, I hope, confirm these good results and reinforce the hope they arouse.
With my respectful and devoted greetings.
Dr Sabine PALIARD-FRANCO 38 10 76 26 4 4 ch de l’Orge, 38 690 CHABONS
PROTOCOL for SERIOUS FORMS (Group II) MACROLIDE TREATMENT C3G (March 27, 2020) Further to my communication yesterday, here are the graphs showing the evolution of the symptoms of the 10 patients who had a severe form of atypical flu syndrome, suggestive of COVID 19, and for whom I thought they should be hospitalized in the short term. They all received Macrolide in combination with C3G (CEFTRIAXONE …More
PROTOCOL for SERIOUS FORMS (Group II) MACROLIDE TREATMENT C3G (March 27, 2020)
Further to my communication yesterday, here are the graphs showing the evolution of the symptoms of the 10 patients who had a severe form of atypical flu syndrome, suggestive of COVID 19, and for whom I thought they should be hospitalized in the short term.
They all received Macrolide in combination with C3G (CEFTRIAXONE) except for patient 2 who received only Ceftriaxone and patients 8, 10 and 11 who received only Macrolide. I have prescribed the macrolide for bronchial inflammation and a C3G for signs of ENT or pneumonia.
We followed the patients every day and recorded the symptoms at the onset of the disease, on the day the treatment was started (noted T) and for the next 3 days (T1,T2,T3).
The symptoms studied were cough, fever, dyspnea of intense and moderate effort, asthenia (3: intense; 2: medium; 1: weak; 0: absent), ENT signs (sore throat, nasal obstruction, anosmia and agueusia).
The cough subsides in all patients rapidly after the start of treatment.
Moderate fever is observed prior to treatment. It normalizes within 48 hours. (the patient in yellow has a fever of other origin because she has a lymphoma).
Intense and moderate exertion dyspnea :
The main symptom being shortness of breath, a rapid improvement of the dyspnea is observed shortly after the introduction of the treatment on both intense and moderate efforts.
The patient 1 in blue (smoker, and carrier of a rheumatic disease) took longer to heal, due to a digestive intolerance of the first macrolide, she is currently (at T+5) completely eupneic.
Patient n°7 in dark blue, (75 years old, diabetic) received the two antibiotics 10d apart, he is currently T+3 for the macrolide and no longer shows any respiratory symptoms.
Asthenia :
After 48 hours of treatment, fatigue clearly diminishes, most patients regain a much better general state.
ENT signs:
All patients had ENT signs which also gave way before the third day of treatment.
The muscular and articular pains:
60% of the patients had muscle or joint pain, which also subsided on the second day of treatment.
Various points:
It should be noted that not all patients were treated at the same stage of the disease (at d7, d7, d14, d6, d22, d16, d13, d5, d3, d18) which rules out the hypothesis of a simple natural elimination of the disease in this healing process.
It is remarkable that patients present many symptoms that all give way at the same time with treatment.
The patients for whom we have the most hindsight no longer show symptoms.
I have used 4 different macrolides, and did not notice any difference in efficacy, only in digestive tolerance.
Conclusion:
This purely clinical study, shows the rapid response of patients suspected of covid 19 at a severe stage, to the combination of a macrolide and a C3G which seems, on the one hand, to stop the degradation of the disease, and on the other hand, to effectively treat all its symptoms in 24 or 48 hours.
It would be interesting to know whether this combination of antibiotics also has a virucidal action in addition to its effectiveness on bacterial superinfection and the resulting inflammation. It is worth knowing whether this treatment should be prolonged as long as the viral excretion persists.
I will send you the synthesis of the Group 1 patient for whom treatment with macrolide alone also appears to be very effective in stopping the progression of the disease and suppressing symptoms.
To date, all the patients I have received with these symptoms (37) are responders.
SUMMARY of 26 March 2020 26 March - Isère In the context of this galloping Covid-19 epidemic that is worrying everyone, to all intents and purposes, I am sharing with you what is happening in our sector: In Châbons, in the Bièvre, like each of my colleagues at the Medical Center, I have already received for 15 days in consultation at least 36 patients for atypical flu syndromes, with symptoms very …More
SUMMARY of 26 March 2020
26 March - Isère
In the context of this galloping Covid-19 epidemic that is worrying everyone, to all intents and purposes, I am sharing with you what is happening in our sector:
In Châbons, in the Bièvre, like each of my colleagues at the Medical Center, I have already received for 15 days in consultation at least 36 patients for atypical flu syndromes, with symptoms very evocative of Covid 19.
Indeed, symptoms such as fever, cough, very inflammatory sore throat, anosmia, agueusia, inaugural digestive disorders and malaise for elderly patients, most of whom had been vaccinated or had already had the seasonal flu, 11 of whom had a severe form. These patients had obviously not been tested, for lack of tests available until a week ago, and these tests were still very rationed, in a lab half an hour away by car(Voiron).
For all severe and varied forms of pneumopathies on subjects at risk (diabetes, obesity, advanced age, cognitive disorders, cardio-vascular terrain or cancer...) I initially prescribed injectable Rocéphine 1 to 2 g/day depending on the corpulence, which quickly brought down the fever and improved certain respiratory symptoms in the patients. However, in spite of this broad-spectrum treatment, there often remained dyspnea with an inflammatory state of the bronchi and rhinopharynx, sibilance, chest tightness, or thick and painful mucus in the upper and lower airways.
At the same time, for a 23 year old with the same flu symptoms, but no risk other than an allergic ground, with fever, cough and worrying worsening of shortness of breath and chest tightness at day 7, with only the clinic to make a decision, I treated him with ZECLAR /Innovair /anti-histamine as for a superinfection of bronchiolitis in infants or atypical spring pneumonia. Treatment that gave a very good result in barely 24 hours on all the symptoms...
Comforted by the rapidity and efficiency of this class of drugs, I added to all my critical cases this prescription of macrolide (ZECLAR, RULID or Zithromax whose bactericidal action on atypical germs and virucidal action is known) which improved within 24 hours the remaining symptoms in all patients, even severe, elderly or polypathological.
In case of shortness of breath and/or stubborn cough, I gladly prescribe a fixed combination of bronchodilator and inhaled corticoid, and an anti-histamine on allergic grounds. (to reduce general inflammation).
I do a daily follow-up of all these cases of atypical flu syndromes and especially for all severe cases.
For those on the verge of hospitalization, I find that under this double treatment, (IM or SC rocephin and macrolide per os, bronchodilators) they no longer have any worrying symptoms or are already cured.
For less severe cases, the macrolide is sufficient and acts from the first 24 hours on cough, fever, myalgia, ENT signs and general condition.
This is amazing.
Whatever the stage of the disease at the beginning of the treatment (D5, D7, D9 or D12) I notice a significant response in less than 48 hours and generally within 24 hours, on the superinfection, and the worrying symptoms, obviously dissociated from the natural evolution of the virus.
Not having access to the tests, I cannot know if the viral load decreases with this treatment, but it is certain that with this treatment one fights effectively against superinfection and inflammation, which is the objective and allowed me to avoid at least 7 hospitalizations, 5 of which were above 75 years old.
I am in the process of preparing a synthesis of the medical data of this population which I will not fail to send to you.
I hope that this will be useful to you, in order to contribute to the outpatient management of group I and II cases and to avoid the switch to hospitalisation and resuscitation.
Pending further treatment instructions for serious cases, such as hydroxychloroquine, which I have not ventured to prescribe, in the meantime, this could perhaps help other patients, particularly elderly patients, or in institutions. Or avoid the use of quinine in case of contraindication or risk of toxicity.
" it is impossible to debunk truth..."-Rafał_O' Vile But this isn't truth, you clown. This post was repeated yesterday by the same user. It was already refuted. Ergo, this is not truth. It is error. "What has indeed been debunked is you and your accomplices..." No it hasn't. Your entire debating strategy is based on making unproven claims like that one. TRY debunking anyone using facts for a …More
But this isn't truth, you clown. This post was repeated yesterday by the same user. It was already refuted. Ergo, this is not truth. It is error.
"What has indeed been debunked is you and your accomplices..." No it hasn't. Your entire debating strategy is based on making unproven claims like that one. TRY debunking anyone using facts for a change, you chattering little monkey.
You always confuse making a claim and proving it with factual support. You always do the former and never the latter. In your case, it's probably deliberate.
"GTV needs mods to stop the liars." When GTV gets moderators, believe me, you'll know it. You especially.
"I have recently uploaded more truth ( about "covid hoax") on my profile..." Good for you, sport! If your "truth" is equal to your comments here it's an utter waste of time. ::D
You should go where you belong. gloria.tv/language/VhNsBNkAXCbW6Ly… There you will be accepted and fit in perfectly with the rest of the dumb pollocks.More
You should go where you belong. gloria.tv/language/VhNsBNkAXCbW6Ly…
There you will be accepted and fit in perfectly with the rest of the dumb pollocks.
Since my Polish is even worse than Rafał_Ordure's English, I can't truly say if the other Polish-language users are racists like Rafal -or as stupid. I suspect at least one of them might be, but I couldn't prove it ;-)
unHoly Cannoli you are not credible and competent person to voice your opinion due to substantial intellectual and spiritual collapse exemplified in your numerous malicious comments. Go and pray if you are Catholic , which I doubt for the comments you make.... ps. I have uploaded on my profile media with voices of real scientists who analyze scientific facts and provide truth which I invite you to …More
unHoly Cannoli you are not credible and competent person to voice your opinion due to substantial intellectual and spiritual collapse exemplified in your numerous malicious comments. Go and pray if you are Catholic , which I doubt for the comments you make.... ps. I have uploaded on my profile media with voices of real scientists who analyze scientific facts and provide truth which I invite you to learn, comprehend and accept... Otherwise you will continue in pertinacious erring and mystification which is diabolical...
As far as the jerk who posted to you earlier I have only this comment. The creature is a degenerate, illogical, dumb pollock desperately seeking attention while possessing the mentality of a worm. The creature appears daily at GTV pretending to know everything about everything unaware that he is seen as an ego-maniacal troll who demonstrates repeatedly to be full of bovine excrement. The creature …More
As far as the jerk who posted to you earlier I have only this comment. The creature is a degenerate, illogical, dumb pollock desperately seeking attention while possessing the mentality of a worm. The creature appears daily at GTV pretending to know everything about everything unaware that he is seen as an ego-maniacal troll who demonstrates repeatedly to be full of bovine excrement. The creature is without knowledge, devoid of logic, simple minded and overall disgusting. The bustard needs a punch in the throat.
You're exactly right, Ultraviolet. I guess if we had a prime minister with 'mommy issues' who married his grandmother we would resort to any, even a debunked, story to manifest pride in our country.
Ultrastooge learn that it is impossible to debunk truth which is now dynamically surfacing out of the cloud of msm hysteria and propaganda with God's help. What has indeed been debunked is you and your accomplices diabolical and pertinacious being in error. GTV needs mods to stop the liars. ps I have recently uploaded more truth ( about "covid hoax") on my profile which I invite you to grasp in …More
Ultrastooge learn that it is impossible to debunk truth which is now dynamically surfacing out of the cloud of msm hysteria and propaganda with God's help. What has indeed been debunked is you and your accomplices diabolical and pertinacious being in error. GTV needs mods to stop the liars. ps I have recently uploaded more truth ( about "covid hoax") on my profile which I invite you to grasp in order to regain your lost sanity...
See FAS.org We can certainly debate and critique the public health response to the covid 19 virus, but it is a real virus. Do you also deny that SARS, MERS, HIV, and H1N1, are also hoaxes?More
See FAS.org
We can certainly debate and critique the public health response to the covid 19 virus, but it is a real virus. Do you also deny that SARS, MERS, HIV, and H1N1, are also hoaxes?
You seemed to have either not read or dismissed the evidence provided at FAS.org. Viruses are single strand micro-organisms not " dead matter". Yes, most people around 95% recover but there are still around 5% who are at higher risk of death due to having other health issues such as high blood pressure, being overweight, asthma, diabetes etc. One can argue that the response should have been more …More
You seemed to have either not read or dismissed the evidence provided at FAS.org.
Viruses are single strand micro-organisms not " dead matter". Yes, most people around 95% recover but there are still around 5% who are at higher risk of death due to having other health issues such as high blood pressure, being overweight, asthma, diabetes etc. One can argue that the response should have been more measured, similar to the approach that Sweden has taken, but spreading misinformation about conspiracy theories and that it's a hoax is dishonest and detrimental to those in the high risk group.
philosopher as to dr. Lanka's definition of virus I reckon he uses the term to make virus distinct form living organism. Thereby, many definitions exclude viruses and possible man-made non-organic life forms, as viruses are dependent on the biochemical machinery of a host cell for reproduction. In order for the scientific process of reaching conclusions to be characterized by objectivity one must …More
philosopher as to dr. Lanka's definition of virus I reckon he uses the term to make virus distinct form living organism. Thereby, many definitions exclude viruses and possible man-made non-organic life forms, as viruses are dependent on the biochemical machinery of a host cell for reproduction. In order for the scientific process of reaching conclusions to be characterized by objectivity one must use more than one source of data, especially since the phenomena is on a macro scale. Moreover, there is proven evidence that COVID - 19 statistics are manipulated by: -WHO to pressure medical industry to inflate "covid" mortality statistics; [www.cdc.gov/…/Alert-2-New-ICD…] [CHANGING DEATH CERTIFICATES | Dr. Yoram Lass] -suspending science of microbiology, natural immunology by contradicting it with vaccination industry, (not only Fauci said America will be locked untill people are vaccinated, also the Polish Minister of Health and other advanced the identical agenda. Coincidence?; ["COVID19": This is not about science] [Dr Peter Gøtzsche reveals corruption in the pharmaceutical industry] -comorbid diseases assigned to "COVID";
