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What does a virus actually look like? This is the first time you can see real (flash-frozen) coronavirus in 3D. Viruses are very small. One thousand of them lined up next to each other would be as …More
What does a virus actually look like?

This is the first time you can see real (flash-frozen) coronavirus in 3D.

Viruses are very small. One thousand of them lined up next to each other would be as thick as a single hair. When scientists look for ways how to fight a virus, they use detailed 3D models. But can we see a virus for real? With cryo-em tomography and the visualization technology developed at nanographics, we can!

Cryo-EM tomography data is pretty noisy, but that didn't stop us. We used machine learning and advanced visualization algorithms to show you the most detailed view of a real SARS-CoV-2 virion, in 3D, directly from the electron microscopy scans.

nanographics.at

Cryo-electron tomography data was provided by Sai Li, Tsinghua University, Beijing, China. Their research about the molecular architecture of SARS-CoV-2 has been published here (the data figures in the video were also adapted from this paper):
sciencedirect.com/…/article/pii/S0092867420311594

Segmentation of the data was done by Nanovisualization Research Group at KAUST led by Ivan Viola:
cemse.kaust.edu.sa/nanovis

SARS-CoV-2 molecular model:
cemse.kaust.edu.sa/…nd-rule-based-mesoscale-models

Paper describing how the model was made:
ieeexplore.ieee.org/document/9224865

Online version of the model + high resolution images:
nanographics.at/projects/sars-cov-2/

Programming and music by Peter Mindek